Text from the Theories section.
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Prevention of COVID-19
The principle of creating a preventive medicines for COVID-19
The most common way of getting SARS-COV-2 is through airborne droplets. And the first cells to be infected are the epithelium of the respiratory tract.
Vaccines and preventive drugs work at different levels. For example, the polio vaccine comes in the form of injections, and it comes in the form of drops that the patient must drink.
In the case of an injection, immunity to polio is built up in the blood. In the case of droplets, in the gastrointestinal tract.
The first place where the polio virus gets during infection is the gastrointestinal tract. If a protective barrier is created there, then the virus will not enter the bloodstream.
Thus, an example of creating a vaccine "no shot" exists.
Today, in 2020, it is not known how high-quality and long-term immunity is formed to coronavirus after vaccination.
There is a risk that not only after vaccination, but also after an illness, a stable long-term immune protection will not be created.
There is an opinion that if these fears are confirmed, then they will have to be vaccinated against coronavirus once a quarter. In this case, the "shot" option becomes inconvenient for the patient and places a heavy burden on the healthcare system.
In this case, the drug may contain some surface structures of the virus, to which the body will develop an immune response.
The medicine can be produced in the form of an aerosol, inhalers and other forms that ensure that the surface structures of the virus enter the respiratory tract.
Even if it is not 100% effective, such a medicine will allow maintaining the strength of immunity to coronavirus, which means not only creating an immunized stratum of the population, but also reducing the number of severe forms of COVID-19.
Dr. Andrey Sokolov